Indigenous Live Attenuated Sheeppox Vaccine SPPV Srin 38/00
Background:
Sheep pox is a severe viral disease in sheep which is economically important in small ruminants. The currently used vaccine strain in the vaccines is RF strain which is an exotic strain, hence a live attenuated sheep pox vaccine using indigenous strain was developed at IVRI for preventive vaccination in sheep population. The vaccine can be manufactured using Vero cell culture which is a continuous cell line.
Technology Details
The vaccine developed uses indigenous sheeppox virus strain [SPPV Srin 38/00] and it is adapted to grow in Vero cell line. Thus, the vaccine production is easily scalable. The vaccine is innocuous, safe, potent and immunogenic [efficacious] for sheep aged more than six months of age. The vaccine has been evaluated both at in house and field. The vaccine protects the vaccinated animals for a period of 40 months, as studied so far under experimental conditions. A patent application has been submitted and the application number is 3834/DEL/2014.