Background:
Bovine anaplasmosis is considered as a major constraint for the dairy sector in tropical and subtropical regions. The diseases is infectious but non?contagious and caused by Anaplasma spp., transmitted through tick bites or by the mechanical transfer of fresh blood from infected to susceptible cattle from biting flies or by blood?contaminated fomites including needles, ear tagging, dehorning and castration equipment. Once cattle of any age become infected with A. marginale, they remain persistently infected carriers for life. The prevalence of anaplasmosis in dairy animals in western Uttar Pradesh is higher than the incidence reports from the different regions of India. The prevalence of bovine anaplasmosis has been reported to be 20.55% in Puducherry Region, 16.67% in Kerala, 22% in Telangana, 46.9% in Haryana, 19.5% in Punjab, 1.2% in Gujarat. In a meta-analysis study on Anaplasma species from India and World from 1988 to 2017 and 1978–2017, respectively, using online databases and offline literatures, the prevalence of Anaplasma species in India and World were 11% and 39%, respectively. The clinical signs such as pyrexia, tachycardia and polypnoea in the bovine anaplasmosis infected animals might be due to the endogenous pyrogens liberated by Anaplasma spp. leading to causing the destruction of erythrocytes, triggering various haemopoietic and thermoregutory centers of the body. Similar to the present study, previous studies also reported the inappetance, pyrexia and enlargement of lymphnodes. It causes severe economic losses to farmers and dairy owners in the form of loss of production in affected animals and the loss of animal itself. It needs to be addressed on priority to make dairy sector sustainable by reducing economic losses occurring due to anaplasmosis and that can be achieved by the availability of cost effective and safe herbal preparation at the farmers door step:
Technology Details:
The present product is a novel polyherbal preparation which has the capacity to target several etiological pathways leading to clearance of the anaplasma from the circulation of infected animals. It also has the capacity to enhance immunity to prevent the settlement of anaplasma in susceptible animal population and can be recommended for prophylactic use. This preparation is cost-effective, more effective than its component medicinal plant and does not have any toxic or side effect with high therapeutic safety margin.