Background:
For control of the duck plague in India, there was no indigenous vaccine available. An attenuated DPV vaccine containing a foreign strain (Holland strain), imported from Netherland during the 1970s is being used for the last 50 years. The vaccine is produced only in 3 to 4 states using embryonated chicken eggs that involves a cumbersome method and is inconvenient for large-scale production. This vaccine is apparently in a crude form containing extraneous tissue materials and it becomes difficult to ascertain the titre of the vaccine virus from batch to batch. Therefore, a cell culture vaccine will be able to solve these problems.:
Technology Details:
ICAR-IVRI has produced the indigenous duck plague cell culture vaccine (DPvac/IVRI-19) by attenuating an Indian duck plague virus isolate (DEV/India/IVRI-2016), which can replace the existing vaccine prepared from a foreign strain. The titre of the vaccine is quite high (10⁷˙⁵/ml) and is suitable for industrial-scale production by cell culture method in which we can have a precisely pure form of the vaccine virus ascertaining uniform titre from batch to batch. This vaccine will meet the entire need of the country plus it will be economic and also has high export potential.