Background:
Lactobacillus fermentum NCDC 400 is technologically important exopolysaccharides (EPS) producing lactic strain that has been found to improve rheological and sensory properties of low-fat Dahi. Besides, it has also exhibited excellent in vitro probiotic properties like tolerance to high bile salt, low pH and adhesion to hydrocarbons. The whole genome sequence of NCDC 400 has been deciphered and several differentially expressed proteins under bile and acid stress has been identified by high throughput proteomic techniques. This strain has shown significant binding of cholesterol by in vitro methods and may be used to develop hypocholesterolemic dairy food to benefit human health
Technology Details:
The invention is related to indigenous probiotic L. fermentum NCDC 400. L. fermentum NCDC 400 exhibits probiotic properties. L. fermentum NCDC 400 binds 85% cholesterol and exhibits immunomodulatory potential.