Background:
Pasteurellosis in cattle and buffalo is a specific form of acute and fatal disease commonly referred to as “Haemorrhagic septicaemia (HS)”. In India, it is caused by Pasteurella multocida serotype ^:B, also denoted as B:2 and it is considered one of the important killer diseasesin bovine. The accepted method of HS control throughout the world is vaccination. Oil adjuvant vaccine (OAV) presently in vogue in India provides an immunity up to one year but it is not liked by filed veterinarians owing to difficult syringeability due to its thick viscosity and also it sometimes causes an untoward reaction like the formation of a lump at the site of inoculation. Keeping in view these backgrounds, a multiple emulsion (ME) HS vaccine was developed which was found efficacious in respect of ease of delivery, lower dose level, and equivalent immunity to OAV in cattle. Due to thin viscosity, its syringeability is easier and its intramuscular administration does not cause any untoward reaction at the site of inoculation.:
Technology Details:
Multiple emulsion HS vaccine obviates the problem of viscosity, syringeability of oil adjuvant HS vaccine. Its 3.5 ml dose for lightweight animals and 4.0 ml dose for heavy animals are adequate to invoke one-year immunity.